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A sedative is anything that makes you sedate — peaceful, calm, tranquil.

In medicine this word refers to drugs that relieve anxiety or tranquilizers that pretty much knock you out.

But other non-pharmaceutical things can have sedative effects, like a soothing cup of tea or a relaxing glass of wine. Review of its effects on cognition, psychomotor performance, mood and sedation.

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Antihistamines can cause drowsiness, which might help you fall asleep for a few nights — but routine use of antihistamines for insomnia isn't recommended.

Chlorpheniramine is an antihistamine that reduces the effects of natural chemical histamine in the body.

Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Antihistamines are classified into two groups – the first-generation (“sedating”) and second-generation (“non-sedating”).

Sedating antihistamines cause sedation as they are highly lipid soluble and readily cross the blood brain barrier.

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